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GNS561 acts as a potent anti-fibrotic and pro-fibrolytic agent in liver fibrosis through TGF-β1 inhibition

Eloïne Bestion , Zuzana Macek Jilkova , Jean-Louis Mège , Marie Novello , Keerthi Kurma et al.
Therapeutic Advances in Chronic Disease, 2020, 11, pp.204062232094204. ⟨10.1177/2040622320942042⟩
Journal articles hal-02977880v1

Neutrophil proteases alter the interleukin-22-receptor-dependent lung antimicrobial defence

Antoine Guillon , Youenn Jouan , Deborah Brea , Fabien Gueugnon , Emilie Dalloneau et al.
European Respiratory Journal, 2015, 46 (3), pp.771-782. ⟨10.1183/09031936.00215114⟩
Journal articles hal-03604696v1

Evidence of early increased sialylation of airway mucins and defective mucociliary clearance in CFTR-deficient piglets

Ignacio Caballero , Bélinda Ringot-Destrez , Mustapha Si-Tahar , Pascal Barbry , Antoine Guillon et al.
Journal of Cystic Fibrosis, 2021, 20 (1), pp.173-182. ⟨10.1016/j.jcf.2020.09.009⟩
Journal articles hal-03556820v1

Substrate-derived triazolo- and azapeptides as inhibitors of cathepsins K and S

Matthieu Galibert , Mylène Wartenberg , Fabien Lecaille , Ahlame Saidi , Sylvie Mavel et al.
European Journal of Medicinal Chemistry, 2018, 144, pp.201-210. ⟨10.1016/j.ejmech.2017.12.012⟩
Journal articles hal-03677245v1

Processing and Maturation of Cathepsin C Zymogen: A Biochemical and Molecular Modeling Analysis

Anne-Sophie Lamort , Yveline Hamon , Cezary Czaplewski , Artur Gieldon , Seda Seren et al.
International Journal of Molecular Sciences, 2019, 20 (19), pp.4747. ⟨10.3390/ijms20194747⟩
Journal articles hal-03677258v1
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Intra-tracheal amikacin spray delivery in healthy mechanically ventilated piglets

Antoine Guillon , François Darrouzain , Nathalie Heuzé-Vourc'H , Antoine Petitcollin , Céline Barc et al.
Pulmonary Pharmacology and Therapeutics, 2019, 57, pp.101807. ⟨10.1016/j.pupt.2019.101807⟩
Journal articles hal-02526680v1

Noninvasive ventilation vs. high-flow nasal cannula oxygen for preoxygenation before intubation in patients with obesity: a post hoc analysis of a randomized controlled trial

Maeva Rodriguez , Stéphanie Ragot , Rémi Coudroy , Jean-Pierre Quenot , Philippe Vignon et al.
Annals of Intensive Care, 2021, 11 (1), pp.114. ⟨10.1186/s13613-021-00892-8⟩
Journal articles hal-03518770v1
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Inhaled bacteriophage therapy in a porcine model of pneumonia caused by Pseudomonas aeruginosa during mechanical ventilation

Antoine Guillon , Jeoffrey Pardessus , Guillaume L’hostis , Cindy Fevre , Céline Barc et al.
British Journal of Pharmacology, 2021, 178 (18), pp.3829-3842. ⟨10.1111/bph.15526⟩
Journal articles hal-03228074v1
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Changes in cardiac arrest patients’ temperature management after the 2013 “TTM” trial: results from an international survey

Nicolas Deye , François Vincent , Philippe Michel , Stephan Ehrmann , Daniel da Silva et al.
Annals of Intensive Care, 2016, 6 (1), ⟨10.1186/s13613-015-0104-6⟩
Journal articles hal-02529485v1

Les valeurs de référence GLI-2012 pour la spirométrie forcée décrivent fidèlement la population européenne et française

V. de Broucker , J.-L. Edmé , L. Plantier , S. Hulo
Revue des Maladies Respiratoires, 2019, 36 (3), pp.287-290. ⟨10.1016/j.rmr.2018.12.005⟩
Journal articles hal-02554963v1

Les chambres d’exposition environnementale (CEE) : un nouvel outil dans la recherche académique et industrielle

N. Khayath , C. Radu , I. Choual , S. Jilani , L. Vecellio et al.
Revue des Maladies Respiratoires, 2018, 35 (4), pp.390-402. ⟨10.1016/j.rmr.2018.01.005⟩
Journal articles hal-02566574v1
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Structure-based design and in vivo anti-arthritic activity evaluation of a potent dipeptidyl cyclopropyl nitrile inhibitor of cathepsin C

Brice Korkmaz , Adam Lesner , Magdalena Wysocka , Artur Gieldon , Maria Håkansson et al.
Biochemical Pharmacology, 2019, 164, pp.349 - 367. ⟨10.1016/j.bcp.2019.04.006⟩
Journal articles hal-03477629v1
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Targeting Aspergillus fumigatus Crf Transglycosylases With Neutralizing Antibody Is Relevant but Not Sufficient to Erase Fungal Burden in a Neutropenic Rat Model

David Chauvin , Michael Hust , Mark Schütte , Adélaïde Chesnay , Christelle Parent et al.
Frontiers in Microbiology, 2019, 10, pp.600. ⟨10.3389/fmicb.2019.00600⟩
Journal articles hal-02439698v1
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Designing inhaled protein therapeutics for topical lung delivery: what are the next steps?

Elsa Bodier-Montagutelli , Alexie Mayor , Laurent Vecellio , Renaud Respaud , Nathalie Heuzé-Vourc'H et al.
Expert Opinion on Drug Delivery, 2018, 15 (8), pp.729-736. ⟨10.1080/17425247.2018.1503251⟩
Journal articles hal-02566478v1

Neutrophilic NLRP3 inflammasome-dependent IL-1β secretion regulates the γδT17 cell response in respiratory bacterial infections

M Hassane , D Demon , D Soulard , J Fontaine , L Keller et al.
Mucosal Immunology, 2017, 10 (4), pp.1056-1068. ⟨10.1038/mi.2016.113⟩
Journal articles hal-03365117v1

Innovative preclinical models for pulmonary drug delivery research

Stephan Ehrmann , Otmar Schmid , Chantal Darquenne , Barbara Rothen-Rutishauser , Josue Sznitman et al.
Expert Opinion on Drug Delivery, 2020, 17 (4), pp.463-478. ⟨10.1080/17425247.2020.1730807⟩
Journal articles hal-03518846v1

A consensus research agenda for optimising nasal drug delivery

Ben Forbes , Rene Bommer , Jonathan Goole , Marie Hellfritzsch , Wilbur de Kruijf et al.
Expert Opinion on Drug Delivery, 2020, 17 (2), pp.127-132. ⟨10.1080/17425247.2020.1714589⟩
Journal articles hal-02566422v1

Proteinase release from activated neutrophils in mechanically ventilated patients with non-COVID-19 and COVID-19 pneumonia

Seda Seren , Lohann Derian , Irem Keleş , Antoine Guillon , Adam Lesner et al.
European Respiratory Journal, 2021, 57 (4), pp.2003755. ⟨10.1183/13993003.03755-2020⟩
Journal articles hal-03556833v1
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Guillaume Desoubeaux , Marilyn Rodriguez , Ellen Bronson , Gayle Sirpenski , Carolyn Cray et al.
Journal of Zoo and Wildlife Medicine, 2018, 49 (3), pp.696-703. ⟨10.1638/2017-0172.1⟩
Journal articles hal-02439676v1

Pneumonies sévères et syndrome de détresse respiratoire aiguë : implication des lymphocytes T non conventionnels

Youenn Jouan , Mustapha Si-Tahar , Christophe Paget
Revue des Maladies Respiratoires, 2019, 36 (4), pp.451-454. ⟨10.1016/j.rmr.2019.03.007⟩
Journal articles hal-03534434v1
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Pneumocystis pneumonia: pitfalls and hindrances to establish a reliable animal model

Adélaïde Chesnay , Christophe Paget , Nathalie Heuzé-Vourc’h , Thomas Baranek , Guillaume Desoubeaux et al.
Journal of Fungi, 2022, 8 (2), pp.129. ⟨10.3390/jof8020129⟩
Journal articles hal-03687287v1

A Functional Variant of Elafin With Improved Anti-inflammatory Activity for Pulmonary Inflammation

Donna Small , Derek Quinn , Arlene Ma Glasgow , Cecilia O'Kane , Danny Mcauley et al.
Molecular Therapy, 2015, 23 (1), pp.24-31. ⟨10.1038/mt.2014.162⟩
Journal articles hal-03655428v1

Molecularly Imprinted Hydrogels Selective to Ribavirin as New Drug Delivery Systems to Improve Efficiency of Antiviral Nucleoside Analogue: A Proof‐of‐Concept Study with Influenza A Virus

Mohamed Ayari , Patrick Favetta , Dawid Warszycki , Virginie Vasseur , Virginie Herve et al.
Macromolecular Bioscience, 2021, pp.2100291. ⟨10.1002/mabi.202100291⟩
Journal articles hal-03557328v1
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Bioorganic Farming Practices as a Source of Atypical Ectoparasitosis

Guillaume Desoubeaux , Marlène Amara , Julien Goustille , Jacques Chandenier
Archives of Dermatology -Chicago-, 2011, ⟨10.1001/archderm.147.12.1458⟩
Journal articles hal-02443816v1

Échec du traitement de Plasmodium falciparum par atovaquone-proguanil

Laetitia Contentin , Leslie Grammatico-Guillon , Guillaume Desoubeaux , Sabine Baron , Thanh Hai Duong et al.
La Presse Médicale, 2011, ⟨10.1016/j.lpm.2011.03.009⟩
Journal articles hal-02443919v1

Seroprevalence Survey for Microsporidia in Common Bottlenose Dolphin (Tursiops truncatus): Example of A Quantitative Approach Based on Immunoblotting

Guillaume Desoubeaux , Roman Peschke , Carolina Le-Bert , Vanessa Fravel , Jeny Soto et al.
Journal of wildlife diseases, 2018, 54, pp.0 - 000. ⟨10.7589/2017-11-287⟩
Journal articles hal-02443882v1
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Therapeutic Antibodies for the Treatment of Respiratory Tract Infections—Current Overview and Perspectives

Alexie Mayor , Adélaïde Chesnay , Guillaume Desoubeaux , David Ternant , Nathalie Heuzé-Vourc'H et al.
Vaccines, 2021, 9 (2), pp.151. ⟨10.3390/vaccines9020151⟩
Journal articles hal-03485350v1

Non-invasive ventilation alternating with high-flow nasal oxygen versus high-flow nasal oxygen alone after extubation in COPD patients: a post hoc analysis of a randomized controlled trial

Arnaud Thille , Rémi Coudroy , Mai-Anh Nay , Arnaud Gacouin , Maxens Decavèle et al.
Annals of Intensive Care, 2021, 11 (1), pp.30. ⟨10.1186/s13613-021-00823-7⟩
Journal articles hal-03518792v1

Nasal high-flow preoxygenation for endotracheal intubation in the critically ill patient: a randomized clinical trial

Christophe Guitton , Stephan Ehrmann , Christelle Volteau , Gwenhael Colin , Adel Maamar et al.
Intensive Care Medicine, 2019, 45 (4), pp.447-458. ⟨10.1007/s00134-019-05529-w⟩
Journal articles hal-03518864v1

Nasal High-Flow Nebulization for Lung Drug Delivery: Theoretical, Experimental, and Clinical Application

Jonathan Dugernier , Grégory Reychler , Laurent Vecellio , Stephan Ehrmann
JOURNAL OF AEROSOL MEDICINE AND PULMONARY DRUG DELIVERY, 2019, 32 (6), pp.341-351. ⟨10.1089/jamp.2019.1524⟩
Journal articles hal-03518863v1