iBraiN Lab (Université de Tours & Inserm) is a multidisciplinary lab, integrating research in Psychiatry, studies in cellular/molecular neuroscience and investigations aimed at developing new technologies for diagnosis and treatment of psychiatric disorders (focusing on methodologies relying on radiopharmaceuticals and ultrasound). It gathers experts in acoustics, chemistry, genetics, philosophy, psychiatry, linguistics, medical imaging, mathematics, neuroscience, philosophy, physics and radiochemistry. Its main objective is to develop personalized therapies for psychiatric disorders, in particular autism and treatment-resistant depression, based on specific biomarkers predicting the efficacy of a given treatment.
The specific objectives of the unit are:
- to improve the comprehension of psychiatric and neurologic disorders by refining diagnosis and treatment
- to develop new imaging technologies and methodologies for the exploration of brain pathologies
- to develop innovative therapies for the treatment of cerebral pathologies
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Camille Dupuy, Pierre Castelnau, Sylvie Mavel, Antoine Lefevre, Lydie Nadal-Desbarats, et al.. SHR/NCrl rats as a model of ADHD can be discriminated from controls based on their brain, blood, or urine metabolomes. Translational Psychiatry, 2021, 11 (1), pp.235. ⟨10.1038/s41398-021-01344-4⟩. ⟨hal-04659136⟩
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