POLY-L-LYSINE-CONJUGATED POROUS SILICON NANOPARTICLES AS LABEL-FREE LUMINESCENT PROBES FOR IN VIVO TIME-GATED IMAGING OF HYDRA VULGARIS
Résumé
In this work, we present the characterization of biocompatible porous silicon nanoparticles (PSiNPs) functionalized with poly-l-lysine following a two-step process. The material exhibits sub-micrometric size, bright photoluminescence (PL) and positive surface charge, coupled with satisfactory morphological and optical stability. Such properties make as-modified PSiNPs effectively exploitable as long-lived photoluminescent probes for rapid time-gated in vivo imaging of Hydra vulgaris.