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Structure: Internal structure identifier : 575191
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High prevalence of clonal hematopoiesis in the blood and bone marrow of healthy volunteers

Hélène Guermouche , Noémie Ravalet , Nathalie Gallay , Caroline Deswarte , Amelie Foucault et al.
Blood Advances, 2020, 4 (15), pp.3550-3557. ⟨10.1182/bloodadvances.2020001582⟩
Journal articles hal-04025523v1
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A variant erythroferrone disrupts iron homeostasis in SF3B1-mutated myelodysplastic syndrome

Sabrina Bondu , Anne-Sophie Alary , Carine Lefevre , Alexandre Houy , Grace Jung et al.
Science Translational Medicine, 2019, 11 (500), pp.eaav5467. ⟨10.1126/scitranslmed.aav5467⟩
Journal articles inserm-02449216v1
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Dibenzofuran Derivatives Inspired from Cercosporamide as Dual Inhibitors of Pim and CLK1 Kinases

Viet Hung Dao , Isabelle Ourliac-Garnier , Cédric Logé , Florence Mccarthy , Stéphane Bach et al.
Molecules, 2021, 26 (21), pp.6572. ⟨10.3390/molecules26216572⟩
Journal articles hal-03428747v1
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ROS Overproduction Sensitises Myeloma Cells to Bortezomib-Induced Apoptosis and Alleviates Tumour Microenvironment-Mediated Cell Resistance

Mélody Caillot , Florence Zylbersztejn , Elsa Maitre , Jérôme Bourgeais , Olivier Hérault et al.
Cells, 2020, 9 (11), pp.2357. ⟨10.3390/cells9112357⟩
Journal articles hal-02983252v1
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Panitumumab and cetuximab affect differently miRNA expression in colorectal cancer cells

Romain Chautard , Laetitia Corset , Sajida Ibrahim , Céline Desvignes , Gilles Paintaud et al.
Biomarkers in Medicine, 2021, Online ahead of print. ⟨10.2217/bmm-2020-0520⟩
Journal articles inserm-03272360v1

Characterization of NADPH Oxidase Expression and Activity in Acute Myeloid Leukemia Cell Lines: A Correlation with the Differentiation Status

Hassan Dakik , Maya El Dor , Joan Leclerc , Farah Kouzi , Ali Nehme et al.
Antioxidants , 2021, 10 (3), pp.498. ⟨10.3390/antiox10030498⟩
Journal articles hal-03251520v1

Outcome of febrile neutropenic patients treated for bacteriuria in hematology

Thomas Delaye , José Miguel Torregrosa Diaz , Maxime Vallée , Maria Pilar Gallego Hernanz , Emmanuel Gyan et al.
Supportive Care in Cancer, 2023, 31 (2), pp.102. ⟨10.1007/s00520-022-07522-4⟩
Journal articles hal-04088053v1

NOX1 and NOX2: two enzymes that promote endothelial-to-mesenchymal transition induced by melanoma conditioned media

Nicolas Clere , Valentin Platel , Diane Lechevalier , Clara Bourreau , Sarah Renault et al.
Pharmacological Research, 2022, pp.106097. ⟨10.1016/j.phrs.2022.106097⟩
Journal articles hal-03542318v1

The French FRACTURE database: A way to improve knowledge on management of children with very rare tumors

Coralie Mallebranche , Yves Reguerre , Brice Fresneau , Nicolas Andre , Claire Berger et al.
Pediatric Blood and Cancer, 2022, 69 (12), ⟨10.1002/pbc.30003⟩
Journal articles hal-04030742v1

Comparison of scoring systems evaluating suitability for intensive chemotherapy in adults with acute myeloid leukemia-a Grand Ouest Against Leukemia (GOAL) study

Christophe Desprez , Jeremie Riou , Pierre Peterlin , Tony Marchand , M Couturier et al.
Journal articles hal-03757984v1
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SK4 oncochannels regulate calcium entry and promote cell migration in KRAS-mutated colorectal cancer

Sajida Ibrahim , Justine Chaigne , Hassan Dakik , Yann Fourbon , Laetitia Corset et al.
Cell Calcium, 2021, 96, pp.102384. ⟨10.1016/j.ceca.2021.102384⟩
Journal articles inserm-03158756v1
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Structure-based design of novel quinoxaline-2-carboxylic acids and analogues as Pim-1 inhibitors

Bruno Oyallon , Marie Brachet-Botineau , Cédric Logé , Pascal Bonnet , Mohamed Souab et al.
European Journal of Medicinal Chemistry, 2018, 154, pp.101-109. ⟨10.1016/j.ejmech.2018.04.056⟩
Journal articles hal-03408667v1

Molecular classification and prognosis in younger adults with acute myeloid leukemia and intermediate-risk cytogenetics treated or not by gemtuzumab ozogamycin: Final results of the GOELAMS/FILO acute myeloid leukemia 2006-intermediate-risk trial

Anne Bouvier , Jean-Francois Hamel , Jacques Delaunay , Eric Delabesse , Pierre-Yves Dumas et al.
European Journal of Haematology, 2021, 107 (1), pp.111-121. ⟨10.1111/ejh.13626⟩
Journal articles hal-03604930v1
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Curcumin and NCLX inhibitors share anti-tumoral mechanisms in microsatellite-instability-driven colorectal cancer

Maxime Guéguinou , Sajida Ibrahim , Jérôme Bourgeais , Alison Robert , Trayambak Pathak et al.
Cellular and Molecular Life Sciences, 2022, 79 (6), pp.article n° 284. ⟨10.1007/s00018-022-04311-4⟩
Journal articles hal-03668944v1

Lien entre reprogrammation métabolique et résistance à l’apoptose induites par le stroma dans les cancers du sein triple négatif

Lisa Nocquet , Kevin Louault , Ophelie Renoult , Jérôme Bourgeais , Agnes Basseville et al.
15ème journées du cancéropôle grand-ouest, Jul 2021, Angers, France
Conference papers inserm-03319390v1

Non-Linear Rituximab Pharmacokinetics and Complex Relationship between Rituximab Concentrations and Anti-Neutrophil Cytoplasmic Antibodies (ANCA) in ANCA-Associated Vasculitis: The RAVE Trial Revisited

Amina Bensalem , Denis Mulleman , Gilles Paintaud , Nicolas Azzopardi , Valerie Gouilleux-Gruart et al.
Clinical Pharmacokinetics, 2019, ⟨10.1007/s40262-019-00826-5⟩
Journal articles hal-02316414v1
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Repurposing of Acriflavine to target Chronic Myeloid Leukemia treatment

R Nehme , R Hallal , M El Dor , F Kobeissy , Fabrice Gouilleux et al.
Current Medicinal Chemistry, 2021, 28 (11), pp.2218 - 2233. ⟨10.2174/0929867327666200908114411⟩
Journal articles hal-03003844v1
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Evidences of a Direct Relationship between Cellular Fuel Supply and Ciliogenesis Regulated by Hypoxic VDAC1-ΔC

Monique Meyenberg Cunha-de Padua , Lucilla Fabbri , Maeva Dufies , Sandra Lacas-Gervais , Julie Contenti et al.
Cancers, 2020, 12 (11), pp.3484. ⟨10.3390/cancers12113484⟩
Journal articles hal-03030384v1
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Expression Profiling of Calcium Channels and Calcium-Activated Potassium Channels in Colorectal Cancer

Sajida Ibrahim , Hassan Dakik , Christophe Vandier , Romain Chautard , Gilles Paintaud et al.
Cancers, 2019, 11 (4), pp.561. ⟨10.3390/cancers11040561⟩
Journal articles inserm-02152189v1

Radiotherapy (WBRT) or Autologous Stem-Cell Transplantation (ASCT) for Primary CNS Lymphoma in Patients 60 Years of Age and Younger: Long-Term Results of the Intergroup Anocef-Goelams Randomized Phase II Precis Study

Caroline Houillier , Luc Taillandier , Roch Houot , Olivier Chinot , Cecile Molucon-Chabrot et al.
Blood, 2021, 138 (Supplement 1), pp.658-658. ⟨10.1182/blood-2021-146389⟩
Journal articles hal-03789542v1
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Acriflavine targets oncogenic STAT5 signaling in myeloid leukemia cells

Rawan Hallal , Rawan Nehme , Marie Brachet‐botineau , Ali Nehme , Hassan Dakik et al.
Journal of Cellular and Molecular Medicine, 2020, 24 (17), pp.10052-10062. ⟨10.1111/jcmm.15612⟩
Journal articles hal-02911576v1
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A comparative study of the capacity of mesenchymal stromal cell lines to form spheroids

Margaux Deynoux , Nicola Sunter , Elfi Ducrocq , Hassan Dakik , Roseline Guibon et al.
PLoS ONE, 2020, 15 (6), pp.e0225485. ⟨10.1371/journal.pone.0225485⟩
Journal articles inserm-02905659v1
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Low-Dose Pesticides Alter Primary Human Bone Marrow Mesenchymal Stem/Stromal Cells through ALDH2 Inhibition

Amélie Foucault , Noemie Ravalet , Joevin Besombes , Frédéric Picou , Nathalie Gallay et al.
Cancers, 2021, 13 (22), pp.5699. ⟨10.3390/cancers13225699⟩
Journal articles hal-03468294v1
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New Quinoxaline Derivatives as Dual Pim-1/2 Kinase Inhibitors: Design, Synthesis and Biological Evaluation

Bruno Oyallon , Marie Brachet-Botineau , Cédric Logé , Thomas Robert , Stéphane Bach et al.
Molecules, 2021, 26 (4), pp.867. ⟨10.3390/molecules26040867⟩
Journal articles inserm-03272339v1
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The specific metabolome profiling of patients infected by SARS-COV-2 supports the key role of tryptophan-nicotinamide pathway and cytosine metabolism

H Blasco , C Bessy , L Plantier , A Lefevre , E Piver et al.
Scientific Reports, 2020, 10 (1), pp.16824. ⟨10.1038/s41598-020-73966-5⟩
Journal articles inserm-03412059v1

Drug delivery system for platinum-based drugs

Giovanna Lollo , Jean-Pierre Benoit , Marie Brachet-Botineau
France, Patent n° : WO 2020/053445 A1. 2020
Patents hal-03142927v1

Outcomes after allogeneic hematopoietic stem cell transplantation for adults with primary mediastinal B cell lymphoma: a SFGM-TC and LYSA study

Baptiste Le Calvez , Benoit Tessoullin , Loic Renaud , Carmen Botella-Garcia , Micha Srour et al.
Acta Oncologica, 2022, 61 (11), pp.1332-1338. ⟨10.1080/0284186X.2022.2130709⟩
Journal articles hal-04084965v1
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No survival improvement in patients with high‐risk multiple myeloma harbouring del(17p) and/or t(4;14) over the two past decades

Thomas Chalopin , Nicolas Vallet , Olivier Theisen , Marlène Ochmann , Mourad Tiab et al.
British Journal of Haematology, 2021, 194 (3), pp.635-638. ⟨10.1111/bjh.17488⟩
Journal articles inserm-03349139v1

The follicle-stimulating hormone signaling network in gonadal cells.

Frédérique Clément , Romain Yvinec , Nathalie Gallay , Laurine Gagniac , Florian Guillou et al.
Alfredo Ulloa-Aguirre; Ya-Xiong Tao. Cellular endocrinology in health and disease, Second Edition, Academic Press, 486 p., 2021, 9780128198018. ⟨10.1016/B978-0-12-819801-8.00020-X⟩
Book sections hal-03128409v1

Daunorubicin and Its Active Metabolite Pharmacokinetic Profiles in Acute Myeloid Leukaemia Patients: A Pharmacokinetic Ancillary Study of the BIG-1 Trial

Guillaume Drevin , Marie Briet , Caroline Bazzoli , Emmanuel Gyan , Aline Schmidt et al.
Pharmaceutics, 2022, 14 (4), pp.792. ⟨10.3390/pharmaceutics14040792⟩
Journal articles hal-03822470v1