Mapping the scientific output of organoids for animal and human modeling infectious diseases: a bibliometric assessment - Université de Tours Accéder directement au contenu
Article Dans Une Revue Veterinary Research Année : 2024

Mapping the scientific output of organoids for animal and human modeling infectious diseases: a bibliometric assessment

Résumé

The escalation of antibiotic resistance, pandemics, and nosocomial infections underscores the importance of research in both animal and human infectious diseases. Recent advancements in three-dimensional tissue cultures, or "organoids", have revolutionized the development of in vitro models for infectious diseases. Our study conducts a bibliometric analysis on the use of organoids in modeling infectious diseases, offering an in-depth overview of this field's current landscape. We examined scientific contributions from 2009 onward that focused on organoids in host‒pathogen interactions using the Web of Science Core Collection and OpenAlex database. Our analysis included temporal trends, reference aging, author, and institutional productivity, collaborative networks, citation metrics, keyword cluster dynamics, and disruptiveness of organoid models. VOSviewer, CiteSpace, and Python facilitated this analytical assessment. The findings reveal significant growth and advancements in organoid-based infectious disease research. Analysis of keywords and impactful publications identified three distinct developmental phases in this area that were significantly influenced by outbreaks of Zika and SARS-CoV-2 viruses. The research also highlights the synergistic efforts between academia and publishers in tackling global pandemic challenges. Through mostly consolidating research efforts, organoids are proving to be a promising tool in infectious disease research for both human and animal infectious disease. Their integration into the field necessitates methodological refinements for better physiological emulation and the establishment of extensive organoid biobanks. These improvements are crucial for fully harnessing the potential of organoids in understanding infectious diseases and advancing the development of targeted treatments and vaccines.
Fichier principal
Vignette du fichier
Yan et al Vet Res 2024.pdf (2.9 Mo) Télécharger le fichier
Origine Fichiers éditeurs autorisés sur une archive ouverte
Licence

Dates et versions

hal-04629505 , version 1 (29-06-2024)

Licence

Identifiants

Citer

Jin Yan, Jean Monlong, Céline Cougoule, Sonia Lacroix-Lamandé, Agnès Wiedemann. Mapping the scientific output of organoids for animal and human modeling infectious diseases: a bibliometric assessment. Veterinary Research, 2024, 55 (1), pp.81. ⟨10.1186/s13567-024-01333-7⟩. ⟨hal-04629505⟩
0 Consultations
0 Téléchargements

Altmetric

Partager

Gmail Mastodon Facebook X LinkedIn More