Olfaction: a potential cognitive marker of psychiatric disorders - Université de Tours Access content directly
Journal Articles Neuroscience and Biobehavioral Reviews Year : 2008

Olfaction: a potential cognitive marker of psychiatric disorders

Boriana Atanasova
  • Function : Author
Jérôme Graux
  • Function : Author
Wissam El-Hage
Caroline Hommet
  • Function : Author
Vincent Camus
Catherine Belzung
  • Function : Author
  • PersonId : 941920


Cognitive deficits are well documented in psychiatric disorders, particularly in schizophrenia and depression. Cognitive activity roots in perceptions. However, research on sensorial alterations in psychiatric conditions has mainly focused on visual or auditory processes and less on olfaction. Here, we examine data on olfactory deficits in psychiatric patients using a systematic review of recent publications. Schizophrenic patients are mainly characterized by no reliable change in odour sensitivity and by a deficit in odour identification, recognition and discrimination. Depressed patients principally exhibit a deficit in the hedonic aspects of this perception, even if, in some case, alterations in sensitivity or identification are also found. Changes in odour perception are also found in dementia and in some neurodegenerative disease, but in this case alterations concern all aspects of the sensorial experience (detection threshold, identification and recognition). Taken together, these data indicate that olfactory abnormalities might be a marker of psychiatric conditions, with a specific pattern for each disease.


Fichier principal
Vignette du fichier
2008_Atanasova_Neurosci_Biobehav_Rev_VF.pdf (384.38 Ko) Télécharger le fichier
Origin : Files produced by the author(s)

Dates and versions

hal-02525204 , version 1 (30-03-2020)



Boriana Atanasova, Jérôme Graux, Wissam El-Hage, Caroline Hommet, Vincent Camus, et al.. Olfaction: a potential cognitive marker of psychiatric disorders. Neuroscience and Biobehavioral Reviews, 2008, 32 (7), pp.1315 - 1325. ⟨10.1016/j.neubiorev.2008.05.003⟩. ⟨hal-02525204⟩


51 View
418 Download



Gmail Facebook Twitter LinkedIn More